Mitochondrial Defense Stack — SS-31 + MOTS-C
For Research Purposes Only. Not intended for human consumption.
The Mitochondrial Defense Stack combines SS-31 and MOTS-C — two of the most studied compounds in mitochondrial research. SS-31 targets the inner mitochondrial membrane directly via cardiolipin interaction, while MOTS-C operates as a mitochondria-derived signaling peptide regulating metabolic stress response from within the mitochondria itself. Together they address mitochondrial function from two distinct angles.
What’s Included
- SS-31 50mg (Elamipretide) — Mitochondria-targeted tetrapeptide. Selectively concentrates in the inner mitochondrial membrane where it interacts with cardiolipin, stabilizing membrane structure and supporting electron transport chain function. One of the most clinically advanced mitochondria-targeted research compounds available.
- MOTS-C 10mg — Mitochondria-derived peptide encoded within the mitochondrial genome. Translocates to the nucleus under metabolic stress to regulate adaptive gene expression, insulin sensitivity, and mitochondrial biogenesis.
Research Rationale
SS-31 addresses structural and functional integrity of the inner mitochondrial membrane — its cardiolipin interaction supports the electron transport chain complexes responsible for ATP production. MOTS-C addresses the signaling and regulatory side of mitochondrial biology — how the mitochondria communicates metabolic stress to the rest of the cell. Research into mitochondrial dysfunction increasingly recognizes that structural support and signaling regulation are both required for comprehensive study of mitochondrial health.
Bundle Specifications
- SS-31: 50mg lyophilized · ≥98% HPLC purity · Lot ZVL-SS3-2501
- MOTS-C: 10mg lyophilized · ≥98% HPLC purity · Lot ZVL-MOT-2501
- Testing: Both independently tested — individual COAs included
- Storage: Store at -20°C. Stable at 4°C short-term.
For laboratory research purposes only. Not approved for human or veterinary use.