Neuroendocrine Stack — Kisspeptin-10 + DSIP

For Research Purposes Only. Not intended for human consumption.

The Neuroendocrine Stack combines Kisspeptin-10 and DSIP — two neuropeptides studied for their regulatory roles within the central neuroendocrine system. Kisspeptin-10 is among the most studied upstream regulators of the hypothalamic-pituitary-gonadal axis. DSIP has been studied in the context of hypothalamic-pituitary-adrenal axis modulation, stress response, and neuroendocrine sleep regulation. Together they address two major neuroendocrine axes through distinct receptor pathways.

What’s Included

• Kisspeptin-10 10mg — Minimum active fragment of kisspeptin, sufficient to activate the GPR54/KISS1R receptor. Research has established it as a key upstream regulator of GnRH neuron activity, LH pulse generation, and HPG axis function. Also studied in metabolic regulation and KISS1 tumor suppressor research.
• DSIP 10mg — Delta Sleep-Inducing Peptide. Beyond sleep architecture research, DSIP has been studied for corticotropin modulation, HPA axis interactions, stress response, and neurotransmitter system effects — establishing it as a broad neuroendocrine research tool.

Research Rationale

The HPG axis (Kisspeptin-10 research) and the HPA axis (DSIP research) are the two primary neuroendocrine stress and reproductive regulatory systems. Research has documented interactions between these axes — HPG axis suppression under chronic stress being one well-documented example. Kisspeptin and DSIP act on different receptors and different hypothalamic populations, making them complementary tools for studying neuroendocrine crosstalk and regulation. Researchers focused on hypothalamic biology, neuroendocrine axis function, or stress-reproductive system interactions will find this a well-supported combination.

Bundle Specifications

• Kisspeptin-10: 10mg lyophilized · ≥98% HPLC purity · Lot ZVL-KIS-2501
• DSIP: 10mg lyophilized · ≥98% HPLC purity · Lot ZVL-DSP-2501
• Testing: Both independently tested — individual COAs included
• Storage: Store at -20°C. Stable at 4°C short-term.

For laboratory research purposes only. Not approved for human or veterinary use.

The information provided here is for educational and research purposes only. All studies referenced are preclinical or in vitro unless otherwise noted. This product has not been evaluated by the FDA and is not intended to diagnose, treat, cure, or prevent any condition.

Researchers should review all available literature and consult appropriate regulatory guidelines before use. Certificate of Analysis documents for each lot are available in our COA Library.